Compare Botox and combination medicines for overactive bladder
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether Botox injections work better than a combination of medicines (anti-muscarinics plus a beta-3 medicine) for people whose overactive bladder symptoms did not improve with one medicine alone. It may help by improving bladder control and reducing urgent, hard-to-hold urine leaks or frequent urination.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have detrusor overactivity, meaning your bladder muscle makes involuntary contractions during bladder filling (checked with a bladder study called urodynamics).
- Your symptoms did not improve with a single medicine option, either an anti-muscarinic or a beta-3 (you may need both for this study).
- You must be able to start the treatment plan that the study assigns (either Botox or combination medicines).
- You should NOT have high leftover urine after you pee (post-void urine retention) before starting treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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