Combination therapy for overactive bladder in women
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This study compares the effectiveness of a combination of medications (solifenacin and mirabegron) versus solifenacin alone with a vaginal estrogen cream for treating women with overactive bladder. It may help those who haven't improved with single medication.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman with overactive bladder, specifically having involuntary bladder contractions.
- You have not improved enough with only one type of medication (antimuscarinics).
- You do not have trouble emptying your bladder completely after urination.
- You do not have medical conditions like narrow-angle glaucoma or uncontrolled high blood pressure that prevent use of the trial drugs.
- You have no history of conditions that prevent using estrogen, such as breast cancer, blood clots, or gallbladder disease.
- You have not used hormone replacement therapy in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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