Chemotherapy after kidney scope for upper tract cancer
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests putting a chemotherapy drug (mitomycin C) directly into the bladder and kidney tube after a diagnostic scope procedure for patients with a suspected upper tract urothelial cancer. It aims to see if this treatment is safe and helps prevent the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a suspected cancer in the lining of the kidney or ureter (upper tract).
- Your doctor plans to do a scope test (ureteroscopy) to look at the cancer.
- The scope test shows a tumor that looks like upper tract urothelial carcinoma.
- You have not had bladder cancer or this type of cancer before.
- You have not had a scope test in the last six months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 3 trial studies whether using gemcitabine (a chemotherapy medicine) in the urinary tract better prevents cancer from coming back than using a simple water wash. It involves people with upper tract urothelial carcinoma who are having curative surgery to remove the affected ureter or kidney tube.
This study is testing whether giving a single dose of chemotherapy directly into the kidney and ureter right after a scope procedure helps prevent upper urinary tract tumors from coming back. It’s for people who are about to have a scope to diagnose or treat a suspected or known tumor in the upper urinary tract.
This trial studies whether a medicine called mitomycin C given as a one-time bladder treatment right after ureteroscopy can reduce later recurrence (measured by urine test results and “IVR rate”). It may help people with non-spreading UTUC who are having endoscopic procedures and are planned for this standard add-on treatment.
This study tests whether giving one dose of chemotherapy placed directly into the bladder after a diagnostic bladder/urinary scope (URS) can help people with a localized upper urinary tract cancer (UTUC). It may help reduce cancer coming back, alongside standard post-scope care.
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