Chemotherapy after scope for upper urinary tract cancer
Part of Kidney & urinary clinical trials.
This study is testing whether giving a single dose of chemotherapy directly into the kidney and ureter right after a scope procedure helps prevent upper urinary tract tumors from coming back. It’s for people who are about to have a scope to diagnose or treat a suspected or known tumor in the upper urinary tract.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a suspected or known cancer in the upper part of your urinary tract (kidney or ureter).
- You are planning to have a scope procedure (ureteroscopy) to look at or treat the tumor.
- You are 18 years or older.
- You are able to carry out daily activities with little help (ECOG score 0-2).
- If you have had bladder cancer, it must be at least 2 years since your last treatment, and you must not be getting bladder wash (irrigation) treatment.
- If you have had a previous upper-tract tumor, it must be more than 1 year since your last treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving chemotherapy before surgery can help people with high-risk upper tract urothelial cancer (a cancer in the kidney or ureter). The goal is to see if it improves outcomes for those who are healthy enough to receive cisplatin-based chemotherapy and undergo surgery.
This trial tests a combination of chemotherapy (gemcitabine) and a targeted drug (Trastuzumab Rezetecan) before surgery to remove the kidney and ureter. It may help shrink the tumor and improve outcomes for people with HER2-positive upper tract urothelial cancer.
This trial tests putting a chemotherapy drug (mitomycin C) directly into the bladder and kidney tube after a diagnostic scope procedure for patients with a suspected upper tract urothelial cancer. It aims to see if this treatment is safe and helps prevent the cancer from coming back.
This study tests whether giving one dose of chemotherapy placed directly into the bladder after a diagnostic bladder/urinary scope (URS) can help people with a localized upper urinary tract cancer (UTUC). It may help reduce cancer coming back, alongside standard post-scope care.
This trial studies whether a medicine called mitomycin C given as a one-time bladder treatment right after ureteroscopy can reduce later recurrence (measured by urine test results and “IVR rate”). It may help people with non-spreading UTUC who are having endoscopic procedures and are planned for this standard add-on treatment.
This Phase 3 trial studies whether using gemcitabine (a chemotherapy medicine) in the urinary tract better prevents cancer from coming back than using a simple water wash. It involves people with upper tract urothelial carcinoma who are having curative surgery to remove the affected ureter or kidney tube.
Hear when a new UTUC trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.