Clin2
NCT05985850Possibly a fitRecruiting

Can cannabis help with opioid addiction treatment?

Opioid Use DisorderMethadoneCannabisFentanyl

Part of Mental health, Pain clinical trials.

This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
24 people
Ages
25 years and older
Study type
Interventional

Who can take part

  • You are at least 25 years old
  • You have been diagnosed with opioid use disorder
  • You started or restarted methadone treatment in the last 30 days
  • You have used cannabis in the past 6 months
  • You agree to use only the cannabis provided by the study and not use any other cannabis or related products
  • You are willing to avoid driving or operating machinery for at least 10 hours after taking the study medication

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06544291Recruiting· Phase 2
THC and CBD for pain and opioid use disorder

This study tests whether a combination of THC and CBD can help people who have both opioid use disorder and chronic low back pain. You would need to be on a stable dose of methadone and have used cannabis at least once in your life.

New Haven, Connecticut
NCT05729932Recruiting· Phase 1
Cannabis and opioid use disorder study

This Phase 1 trial studies cannabis in people with opioid use disorder. The goal is to better understand how it may affect opioid use disorder, while monitoring safety.

Lexington, Kentucky
NCT07668635Not yet recruiting· Phase 1
Testing cannabis for reducing opioid withdrawal and use

This study tests whether cannabis can help ease opioid withdrawal and reduce opioid use. Participants will stay at the hospital for about 6 weeks to receive the study treatment and be closely monitored.

Lexington, Kentucky
NCT07148206Not yet recruiting· Phase 3
Cannabis-like medicines for withdrawal symptoms when starting buprenorphine

This trial tests whether two cannabis-like medicines, dronabinol and Epidiolex, can help reduce withdrawal symptoms and other discomforts people may feel when they first start taking buprenorphine for opioid use disorder. If you've recently started buprenorphine and still have symptoms, this study might offer extra relief.

The Bronx, New York
NCT04161066Recruiting· Phase 1
Psilocybin plus buprenorphine to help opioid use disorder symptoms

This Phase 1 study tests how adding psilocybin to a standard opioid treatment (buprenorphine-naloxone) affects recovery and symptoms in people with moderate-to-severe opioid use disorder. It may help researchers understand whether this combination is safe and beneficial alongside medication for opioid withdrawal and cravings.

Madison, Wisconsin
NCT06323824Recruiting· Phase 4
Methadone vs. buprenorphine for opioid use disorder treatment

This study compares two medications, methadone and buprenorphine, to see which helps people stay in treatment for opioid use disorder. You may be eligible if you are starting a new treatment episode.

Oakland, California

Hear when a new Opioid Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.