Testing montelukast for gulf war illness
Treatments studied
Part of Injuries & trauma clinical trials.
This study tests whether montelukast, a medication for asthma and allergies, can help improve thinking problems in veterans with Gulf War Illness. The trial involves taking the study drug or a placebo for 8 weeks, with weekly phone check-ins.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a veteran who served in the Persian Gulf region between August 1990 and December 1991.
- You have been diagnosed with Gulf War Illness (GWI) with symptoms like fatigue, pain, brain fog, stomach issues, breathing problems, or skin problems that started during or after deployment and lasted at least 6 months.
- You have self-reported trouble with thinking or memory (a score of 40 or less on a standard questionnaire).
- You can attend two in-person study visits and have reliable phone service for 8 weekly calls.
- You are not currently taking montelukast and have not taken it in the past 6 months.
- You do not have other major health conditions (such as uncontrolled diabetes, heart disease, or certain cancers) that would interfere with the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether replacing growth hormone can improve symptoms in veterans with Gulf War Illness and adult growth hormone deficiency. It also checks that the treatment is safe for people with stable medications and hormone regimens.
This Phase 3 study tests whether following a study diet can improve symptoms of Gulf War illness. It may help people by confirming whether diet changes are an effective treatment.
This study tests whether a natural supplement called Pycnogenol (from French maritime pine bark) can help with symptoms of Gulf War Illness. It lasts 12 months and is for male veterans who have already been in a related study.
This early-stage study tests the treatment called NAC to understand how it may work in veterans with Gulf War illness–related symptoms like fatigue and brain/mood changes. It also looks at “mechanisms,” meaning what’s happening in the body and brain while you’re in the study.
This study checks blood tests to see whether they can help confirm Gulf War illness. If you qualify as having Gulf War illness (or are a similar Gulf War veteran without it), your blood and health information may be used to validate these marker tests.
This study tests whether acupuncture can help relieve Gulf War Illness symptoms like fatigue, mood or thinking problems, and muscle or joint pain. You may be able to join if you were deployed to the Gulf region and have had these symptoms for more than 6 months.
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