Studying how endometrial cancer develops
Part of Cancer, Women’s health & pregnancy clinical trials.
This study is looking at how the lining of the uterus changes over time, from normal to precancerous to cancer. By analyzing your tissue samples, the researchers hope to find better ways to detect and treat endometrial cancer early.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of normal endometrium, atypical hyperplasia, or endometrial cancer (confirmed by a pathologist).
- You must have had a hysteroscopic surgery or hysterectomy to get that diagnosis.
- You must be willing to have your tissue and data used for genetic and other advanced tests.
- You must not have any other cancers elsewhere in your body.
- You must be able to follow study instructions and give your informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at combining genetic testing with surgical exams to better understand endometrial cancer. It may help doctors see which treatments could work best for you.
This study uses advanced genetic testing (next-generation sequencing) to look at the molecular makeup of endometrial cancer or its rare subtype, carcinosarcoma. The goal is to better understand the cancer and possibly guide more personalized treatment.
This trial studies tumor DNA in blood and tissue from people with aggressive endometrial cancer to better understand the disease. You donate samples during surgery and follow-up visits.
This study looks for “methylated DNA markers” (special DNA patterns) to help detect endometrial, ovarian, and cervical cancers, and to support doctors around planned procedures. It may help find cancer earlier or better sort out who needs closer treatment.
This study is watching and collecting data from patients with rare gynecologic tumors. It uses special tests on your tumor samples to learn more about these cancers, which may help find better treatments in the future.
This study will look at how certain genetic changes (in the TP53 gene and in chromosome stability) affect endometrial cancer that has a specific molecular profile (pMMR/MSS and no POLE mutation). It aims to understand why these tumors behave the way they do.
Hear when a new the Dynamic Evolution of Endometrial Carcinogenesis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.