Clin2
NCT06033131Possibly a fitRecruiting

Metformin to help prolong pregnancy in preterm preeclampsia

Preeclampsia

Part of Women’s health & pregnancy clinical trials.

This trial tests whether metformin, a common diabetes medication, can help women with preeclampsia stay pregnant longer before delivery. If you have been diagnosed with preeclampsia and your doctors are monitoring you without immediate delivery, this study might be an option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
294 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with preeclampsia (high blood pressure with protein in your urine).
  • Your doctors have decided it is safe to wait and monitor your condition rather than deliver right away.
  • You are at least 18 years old.
  • You are between 22 weeks and 33 weeks plus 6 days pregnant with a single baby.
  • You do not have a medical condition that makes metformin unsafe, such as severe kidney problems or type 1 diabetes.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05676476Recruiting
Tested extra blood-pressure control to extend pregnancy in preeclampsia

This trial studies whether using specific blood-pressure medicines can help people with non-severe preeclampsia stay pregnant longer. It aims to improve outcomes by treating blood pressure early while monitoring you and the baby closely.

Birmingham, Alabama
NCT07193680Recruiting
Managing term preeclampsia with angiogenic factors

This study tests whether measuring certain proteins in the blood (angiogenic factors) can help doctors better manage preeclampsia in women who are 36 to 38 weeks pregnant. The goal is to see if this approach can safely delay delivery and improve outcomes for both mother and baby.

Barcelona, BARCELONA
NCT07282171Recruiting· Phase 1
Study of CBP-4888 for preterm preeclampsia in hospitals

This trial tests a new medicine, CBP-4888, for pregnant women hospitalized with preeclampsia starting after 20 weeks. The goal is to see if it's safe and how it works for you and your baby, who will be followed for up to 24 months after birth.

Parkville, Victoria
NCT07384936Not yet recruiting
Testing Topefilgrastim to prevent preeclampsia in high-risk pregnancy

This study tests whether a medication called Topefilgrastim can help prevent preeclampsia in pregnant women at high risk. It is given as an injection during early pregnancy (weeks 11-13) and aims to reduce the chances of developing this serious condition.

Lanzhou
NCT07448597Recruiting· Phase 4
Progesterone for preventing preeclampsia

This trial tests if taking progesterone early in pregnancy can help prevent preeclampsia, a condition of high blood pressure. You may qualify if you are over 18, speak English, and are less than 12 weeks pregnant.

Charleston, South Carolina
NCT07665853Not yet recruiting· Phase 3
Aspirin to prevent preeclampsia in high-risk pregnancies

This trial tests whether a shorter course of aspirin can safely prevent preeclampsia in pregnant people who are already at high risk and taking daily aspirin. It aims to find the best time to stop the medication while still protecting both mother and baby.

Vienna

Hear when a new Preeclampsia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.