Clin2
NCT06040970Likely a fitRecruiting

Sacituzumab govitecan plus cisplatin for recurrent ovarian/endometrial cancer

Ovarian CancerMalignant Neoplasm of Uterus

Treatments studied

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This trial tests a combination of two drugs—sacituzumab govitecan and cisplatin—for women with ovarian or endometrial cancer that has come back after responding to platinum chemotherapy. The goal is to see if the combination works better than current options.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
54 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have ovarian or endometrial cancer that came back after at least 6 months from your last platinum chemotherapy.
  • You are a woman 18 years or older.
  • You are healthy enough for daily activities (able to care for yourself) and expected to live at least 12 more weeks.
  • Your cancer can be seen on a CT scan (measurable or evaluable disease).
  • Your blood counts and kidney/liver function are within a certain range (doctors will check).
  • You have not had prior treatment with the study drug (sacituzumab govitecan) or similar drugs.
  • You must not be pregnant or breastfeeding, and you must use effective birth control during and 6 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07063212Recruiting· Phase 2
Sacituzumab govitecan plus cetuximab for head and neck cancer

This trial tests a combination of two drugs—sacituzumab govitecan and cetuximab—for people with advanced head and neck cancer that has gotten worse after immunotherapy. The goal is to see if this new treatment can shrink or slow the cancer.

Basking Ridge, New Jersey
NCT06477419Recruiting· Phase 2
Sacituzumab govitecan for mesothelioma after prior treatment

This study tests a drug called sacituzumab govitecan (a targeted therapy that delivers chemotherapy directly to cancer cells) for people with mesothelioma that has already been treated with other therapies. The goal is to see if the drug can shrink tumors and help control the disease.

Basking Ridge, New Jersey
NCT06065371Recruiting· Phase 1
Sacituzumab govitecan plus capecitabine for advanced GI cancers

This trial tests a combination of two drugs—sacituzumab govitecan (targeted therapy) and capecitabine (chemotherapy)—for people with advanced stomach, colon, or pancreatic cancer that has stopped responding to standard treatments.

Detroit, Michigan
NCT07674615Not yet recruiting· Phase 1
Study of a targeted drug for advanced or recurrent ovarian cancer

This trial tests a drug called IMMU-132, which targets a protein (TROP-2) found on some ovarian cancer cells. It may help people whose cancer has returned or spread and who have not responded well to standard treatments.

Shanghai, Shanghai Municipality
NCT07504588Recruiting· Phase 2
Comparing two drug combinations for recurrent ovarian cancer after PARP inhibitor treatment

This trial tests whether a new drug combination (sacituzumab govitecan plus bevacizumab) works better than the usual chemotherapy for ovarian cancer that has come back after platinum treatment and PARP inhibitor maintenance. It may offer a new option for people with certain genetic markers (BRCA mutations or HRD).

Fayetteville, Arkansas
NCT07314619Not yet recruiting· Phase 2
Sacituzumab and bevacizumab for platinum-resistant ovarian cancer

This trial tests two targeted drugs — sacituzumab tirumotecan (which attacks cancer cells) and bevacizumab (which cuts off blood supply to tumors) — for ovarian cancer that has stopped responding to platinum chemotherapy. The goal is to see if this combination helps shrink or slow the cancer.

Zhengzhou, Henan

Hear when a new Ovarian cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.