Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,959 recruiting studies in this area right now.
By phase
- Not applicable5,619
- Phase 2645
- Phase 1582
- Phase 3403
- Phase 4322
- Phase 1/Phase 2299
- Phase 2/Phase 389
Top conditions
- Obesity653
- Ovarian Cancer339
- Pancreatic Cancer294
- Type 2 Diabetes276
- Diabetes207
- Diabetes Mellitus190
- Diabetes Mellitus, Type 2186
- Hypertension143
- Metabolic Syndrome138
- Type 1 Diabetes131
- Cardiovascular Diseases114
- Obesity & Overweight113
- Breast Cancer110
- Amyotrophic Lateral Sclerosis108
- Overweight102
- Pancreas Cancer94
- Colorectal Cancer90
- Endometrial Cancer88
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S57
- University of Colorado, Denver57
- Assistance Publique - Hôpitaux de Paris55
- M.D. Anderson Cancer Center42
- National Taiwan University Hospital42
- Massachusetts General Hospital40
- Cairo University39
- IRCCS Azienda Ospedaliero-Universitaria di Bologna39
- Eli Lilly and Company38
Where studies are running
- California531
- Maryland181
- Alabama173
- Arizona172
- Texas164
- Florida160
- New York156
- Massachusetts150
- Pennsylvania117
- Colorado113
Recruiting studies7,959 total
- NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT00027274Recruiting
Cancer risk in inherited bone marrow failure syndromes
This study looks at why people with inherited bone marrow failure syndromes (rare genetic conditions affecting blood cell production) have higher cancer risk. Researchers want to understand the genetic and medical factors that increase cancer likelihood, which could help doctors monitor and protect affected patients and their families.
Bethesda, MarylandAges 1 day–100 years - NCT00344331Recruiting
Testing blood and MRI markers for Niemann-Pick type C
This study measures biochemical (blood/biologic) markers and may use clinical evaluation and MRI to better understand Niemann-Pick disease type C. It could help improve how the condition is tracked and understood over time.
Bethesda, MarylandAges 1 day–120 years - NCT00029965Recruiting
Understanding rare storage diseases over time
This study follows people with rare genetic conditions (GM1, GM2, sialidosis, or galactosialidosis) that affect how the body breaks down certain substances in cells. Researchers track how these diseases progress to better understand them and potentially help future patients.
Bethesda, MarylandAges 1 day–100 years - NCT00250159Recruiting
Natural history study for hormone-related excess androgen
This study follows people who may have too much “androgen” (a hormone) to learn what causes it and how it changes over time. You may be followed even if the exact cause is not yet known, and your results may help doctors better understand these conditions.
Washington D.C., District of ColumbiaAges 1 day–99 years - NCT06970457Recruiting
Exercise, body fat, and hormones in men
This study investigates how exercise affects sex hormones in men with different body types. Participants will engage in a supervised exercise program to see how it interacts with body composition.
Stillwater, OklahomaAges 18–79 - NCT06964880Recruiting
Peer support program for obesity and muscle loss awareness in college students
This study tests whether a peer support program (using videos and messages) can help college students become more aware of obesity and muscle loss. It is for students at one university in central Taiwan who are slightly overweight or have higher body fat, and who are otherwise healthy.
TaichungAges 18–25 - NCT06714240Recruiting
Extra protein to support muscle strength in ICU
This study tests whether giving extra protein through a feeding tube can help ICU patients maintain muscle strength. It may be an option for people who are expected to stay in the ICU for at least a week and need a breathing machine.
Hasselt, LimburgAges 18 years+ - NCT06480305Recruiting
Evening snacks and pre-breakfast intake in healthy men
This study looks at how eating an evening snack before bed and having a small pre-breakfast meal affects sleep quality, heart rate, and stress levels in healthy men. It may help you understand how meal timing affects your body.
Islamabad, Punjab ProvinceAges 30–50 - NCT06339996Recruiting
Male supplement for better sperm quality and aging
This study tests whether a specially designed supplement for men can improve sperm quality and help with age-related fertility issues. It may be an option if your semen analysis shows below-normal results.
Kaohsiung CityAges 30–50 - NCT06254638Recruiting
Moveschool: Boosting physical activity during school
This trial tests a school-based program designed to increase physical activity levels during the school day for teenagers. It aims to see if adding more movement into the school routine can improve health and activity habits.
CáceresAges 11–16 - NCT05421143Recruiting
Test a personal plan to help people take medicines safely after discharge
This study is designing and testing a person-centered plan to help you use your medicines correctly when you leave the hospital. It involves you, your family or caregiver, and your usual healthcare team to reduce medication problems across care settings.
OsloAges 18 years+ - NCT04909606Recruiting
Nurse coaching to prevent steroid treatment complications
This study tests a nurse-led program to help prevent complications from taking corticosteroids (steroid medicines) for a long time. If you’ve recently started high-dose steroid treatment, this could offer structured support to reduce risks.
BrestAges 18 years+ - NCT07792876Recruiting
Testing ketone and carbohydrate supplements in trained cyclists
This study is testing how taking ketone and carbohydrate supplements affects performance in trained cyclists. It is looking for male amateur cyclists who train regularly and have a high fitness level.
Ribeirão Preto, São PauloAges 20–50 - NCT04677816RecruitingPhase 2
Vitamin D for a better response to chemotherapy
This study tests whether taking high-dose vitamin D before and during chemotherapy helps eliminate more cancer before surgery in people with triple-negative breast cancer who are low in vitamin D.
Winston-Salem, North CarolinaAges 18 years+ - NCT07792837Recruiting
Online intuitive eating program for pregnant women with obesity
This study tests an online program that helps pregnant women with obesity learn to eat intuitively, which means listening to their body's hunger and fullness signals instead of dieting. The goal is to support their well-being during pregnancy.
San Diego, CaliforniaAges 18 years+ - NCT07707830Recruiting
Thyroid and body health assessment for adults with low thyroid function
This study looks at how an underactive thyroid (hypothyroidism) affects internal organs, muscles, and bones. It uses ultrasound and physical measurements to understand these effects, which may help improve care.
AndijanAges 18–59 - NCT07417124RecruitingPhase 1
Study of SNS851 for people with high liver fat
This study tests a new medicine called SNS851 in healthy volunteers to see if it is safe and tolerable. It may help people with high liver fat, though it is not yet known if it works.
MelbourneAges 18–60 - NCT06302348RecruitingPhase 3
Sepiapterin study for phenylketonuria
This study tests a new medicine called sepiapterin to see if it can help control blood phenylalanine levels in people with PKU. The trial aims to find a safe and effective dose for different age groups.
Indianapolis, IndianaAges Up to 9 years - NCT07254364Recruiting
Wearable sensor to check insulin without needles
This study tests a wearable device that may measure insulin levels without needing blood draws. If you have type 1 diabetes, you might help researchers learn if this new sensor works for daily monitoring.
College Station, TexasAges 18–90 - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT07553325Recruiting
Shared Decision-Making Support for Prediabetes
This study tests a new way to help patients with prediabetes (slightly high blood sugar) make informed choices about their health using personalized risk information. The goal is to see if this approach helps patients take action to prevent or delay type 2 diabetes.
Frederick, MarylandAges 18–75 - NCT06555952Recruiting
Grape seed extract for blood pressure and heart health
This trial tests whether a grape seed extract can help lower blood pressure in people with mildly high blood pressure and slightly elevated blood sugar. It's designed for adults aged 40-60 who are not on blood pressure or diabetes medications.
Chicago, IllinoisAges 40–60 - NCT06909565RecruitingPhase 4
Inclisiran to prevent heart and leg events after artery procedure
This study tests whether a twice-yearly injection called inclisiran can prevent heart attacks, strokes, or leg complications in people who recently had a procedure to open a blocked artery. You may be eligible if you had a heart or leg artery procedure within the last two weeks.
Alexander City, AlabamaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,959 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,428 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.