Misoprostol use in hysteroscopic fibroid removal
Part of Women’s health & pregnancy clinical trials.
This trial tests if misoprostol, a medication that softens the cervix, helps make hysteroscopic myomectomy (a procedure to remove fibroids through the vagina) easier or safer. It is for women with small, inner-womb fibroids who are scheduled for this surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 20 and 55 years old.
- You are scheduled to have a hysteroscopic myomectomy for fibroids inside the womb.
- You have 1 or 2 small fibroids (less than 4 cm) that are type 0, 1, or 2 (meaning they are fully or partly inside the womb cavity).
- You are not past menopause.
- You are not allergic to misoprostol.
- You do not have severe lung or heart disease, a current pelvic infection, or a positive pregnancy test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if giving misoprostol (a medication given as a rectal suppository) during a hysteroscopic myomectomy helps reduce the amount of fluid used during the surgery. It may lead to a safer procedure for removing small uterine fibroids.
This trial tests if giving misoprostol before surgery can reduce blood loss during the removal of uterine fibroids (non-cancerous growths). It is for women who need laparoscopic or open surgery for their fibroids.
This study compares two ways to prepare the cervix before a hysteroscopy (a camera test) in postmenopausal women. It aims to see which method makes the procedure easier and more comfortable.
This study evaluates whether a specific scoring system can predict how well hysteroscopic surgery (a minimally invasive procedure using a thin camera inserted through the cervix) will work for removing small fibroids that cause heavy bleeding, pelvic pain, or infertility. The goal is to help doctors better predict surgical success before the procedure.
This study compares two ways of using misoprostol (a medicine that helps the uterus contract) to prevent heavy bleeding after a C-section. One group gets a vaginal tablet before the surgery, the other gets a tablet under the tongue after the surgery.
This trial tests if giving a medication called misoprostol as a rectal suppository can help reduce bleeding during a planned cesarean section. If you are having a planned cesarean and are generally healthy, this study might be an option for you.
Hear when a new Hysteroscopic Myomectomy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.