Clin2
NCT06765473Possibly a fitNot yet recruiting

Misoprostol before or after C-section to prevent bleeding

Postpartum Hemorrhage

Treatments studied

Part of Women’s health & pregnancy clinical trials.

This study compares two ways of using misoprostol (a medicine that helps the uterus contract) to prevent heavy bleeding after a C-section. One group gets a vaginal tablet before the surgery, the other gets a tablet under the tongue after the surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
400 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 37 weeks pregnant (full-term).
  • You are planning a scheduled (elective) C-section.
  • Your baby's heartbeat is normal on a monitor.
  • You do not have placenta previa, high blood pressure in pregnancy, or a bleeding disorder.
  • You have not had heavy bleeding after a previous birth, and are not on blood thinners or long-term steroids.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07188207Not yet recruiting
Rectal misoprostol to reduce blood loss during planned cesarean

This trial tests if giving a medication called misoprostol as a rectal suppository can help reduce bleeding during a planned cesarean section. If you are having a planned cesarean and are generally healthy, this study might be an option for you.

NCT05245227Recruiting· Phase 3
Prevent heavy bleeding after birth with two medicines versus one

This study tests whether using two medicines at the same time after delivery works better than using one medicine to prevent early heavy bleeding. It may help reduce the chance of postpartum hemorrhage soon after birth.

Stony Brook, New York
NCT07353281Not yet recruiting
Comparing two drugs to prevent heavy bleeding after childbirth

This trial compares two medications, carbetocin and misoprostol, to see which works better at preventing heavy bleeding (postpartum hemorrhage) after a vaginal delivery. It is for women who have one or more risk factors for heavy bleeding.

NCT06285409Recruiting
Uterus contraction medicine study during planned C-sections

This study looks at how well different doses of a contraction medicine work after an initial dose in women having a planned C-section. It may help find the best way to prevent bleeding after birth.

Toronto, Ontario
NCT06946914Recruiting· Phase 4
Misoprostol before planned c-section

This trial tests if giving misoprostol before a planned c-section can help reduce bleeding. It might make the surgery safer for women who meet certain criteria.

Kafr Ash Shaykh, Egypt
NCT06882824Recruiting
Preventing bleeding during fibroid surgery with misoprostol

This trial tests if giving misoprostol before surgery can reduce blood loss during the removal of uterine fibroids (non-cancerous growths). It is for women who need laparoscopic or open surgery for their fibroids.

Clermont-Ferrand, Clermont-Ferrand

Hear when a new Postpartum Hemorrhage trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.