Psilocybin and buprenorphine for opioid use disorder
Treatments studied
Part of Mental health clinical trials.
This study tests whether adding psilocybin (a psychedelic medicine) to buprenorphine (a medication for opioid use disorder) can help people stop using opioids and stay in recovery. It is for people who have already been on buprenorphine but are still using other opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 70 years old.
- You have been diagnosed with opioid use disorder.
- You have taken buprenorphine before and are either starting it now, started it in the last 3 weeks, or are on it but still using other opioids.
- You are not taking antidepressants or other medications that affect serotonin (like SSRIs or MAO inhibitors).
- You have not used psychedelic drugs (like psilocybin, LSD) in the past year.
- You have stable housing, can read and speak English, and are not at high risk for suicide.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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