Clin2
NCT06084481Possibly a fitRecruiting

Study of a new drug for advanced solid tumors

Hepatocellular CarcinomaPancreatic Ductal AdenocarcinomaBiliary Tract CancersEsophageal Squamous Cell CarcinomaTriple Negative Breast CancerHormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast CancerHead and Neck Squamous-Cell CarcinomaPlatinum Resistant High Grade Epithelial Ovarian Cancer

Treatments studied

Part of Cancer, Digestive system, Skin clinical trials.

This study tests a new intravenous drug called ABBV-400 in people with certain advanced solid tumors that have not responded to other treatments. The goal is to see if it can slow or stop tumor growth and to check for side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
325 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have one of these cancers: liver, pancreatic, bile duct, esophageal, breast, head and neck, or ovarian cancer that has spread or cannot be removed by surgery.
  • Your cancer must be measurable on scans (like CT or MRI).
  • You must have had prior cancer treatment (chemotherapy, radiation, immunotherapy, etc.) and stopped it at least 28 days before starting the study drug.
  • You have no current or past lung problems like interstitial lung disease or pneumonitis that needed steroids.
  • You have not had untreated brain metastases, or if you have had brain metastases, they are stable and you do not need steroids for brain swelling.
  • You do not have another active cancer except for certain non-melanoma skin cancers or other early-stage cancers.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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