Fruquintinib, sintilimab, and chemo for advanced stomach cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of two targeted drugs (fruquintinib and sintilimab) plus standard chemotherapy for people with advanced stomach or gastroesophageal junction cancer that has not been treated before. The goal is to see if this combination can help shrink or control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery or has spread to other parts of the body.
- You have not received any previous treatment for your advanced cancer (but prior chemo after surgery more than 6 months ago may be okay).
- You are between 18 and 75 years old.
- You are generally active and able to take care of yourself (ECOG score 0 or 1).
- Your cancer is HER2-negative (a specific protein test).
- You have at least one tumor that can be measured on a scan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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