Combination immunotherapy and targeted therapy for advanced gastric cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a combination of three drugs—adebrelimab (an immunotherapy), fruquintinib (a targeted therapy to cut off blood supply to the tumor), and a chemotherapy (paclitaxel or albumin-bound paclitaxel)—in people with advanced stomach/gastric cancer whose disease has worsened after one prior chemotherapy. The goal is to see if this new mix can help control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have advanced (stage 4) or locally advanced stomach/gastric cancer that has spread or cannot be removed with surgery.
- You have already tried one chemotherapy treatment for this cancer and it stopped working, or the cancer came back within 6 months of finishing chemotherapy after surgery.
- You have not been treated with a PD-1 or PD-L1 inhibitor (like Keytruda, Opdivo, etc.) for this cancer.
- Your blood counts, kidney, and liver function are within acceptable limits (as checked by blood and urine tests).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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