Fasting and exercise for advanced breast cancer
Part of Cancer clinical trials.
This study looks at whether fasting overnight and/or doing exercise can help improve fatigue and other quality-of-life measures in women with advanced hormone receptor positive breast cancer who are already taking a CDK4/6 inhibitor. Participation may involve following a fasting or exercise plan for a period of time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are female.
- You are postmenopausal (or have had your ovaries suppressed).
- You have advanced (metastatic or locally advanced) breast cancer that is hormone receptor positive (ER+ and/or PR+).
- You have started a CDK4/6 inhibitor (like palbociclib, ribociclib, or abemaciclib) within the last 90 days.
- You have not been regularly fasting (12+ hours overnight) in the last 3 months.
- You have not been regularly exercising (more than 90 minutes moderate or 45 minutes vigorous per week) in the last 3 months.
- You have not been doing resistance training (like weight lifting) 2 or more days per week in the last 3 months.
- You have approval from your cancer doctor to participate.
- You do not need supplemental oxygen.
- You do not have unstable heart disease.
- You do not have insulin-dependent diabetes.
- You are able to walk 2 blocks without assistance (cane allowed).
- You do not have a shift work schedule (evening, night, or rotating shifts) in the last 3 months.
- You have no history of a clinical eating disorder.
- You do not have unstable bone metastases.
- You have no severe medical or psychiatric condition or medication that would make the study unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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