Clin2
NCT06126744Worth exploringRecruiting

Study of a virus therapy for recurrent brain cancer

Recurrent High Grade Glioma

Part of Cancer clinical trials.

This trial tests a virus-based treatment called MVR-C5252 for people whose high-grade glioma or glioblastoma has come back after standard therapy. The virus is injected directly into the tumor to try to kill cancer cells and boost the immune system. The goal is to see if it is safe and if it can shrink the tumor.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
51 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • Your brain tumor has come back after standard treatment, is at least 1 centimeter in size, and no larger than 3 centimeters
  • Your tumor is in a location where a thin tube (catheter) can be safely placed into it, away from critical brain areas
  • You have already had radiation therapy and temozolomide chemotherapy and your tumor did not respond
  • You have good kidney, liver, and blood cell counts as shown by lab tests
  • You are able to have an MRI scan of the brain

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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