Clin2
NCT06140576Possibly a fitNot yet recruiting

Drug combination for advanced triple negative breast cancer

Breast Neoplasms

Treatments studied

Part of Cancer, Skin clinical trials.

This study tests a combination of three drugs—lenvatinib (a targeted therapy that blocks blood vessel growth), sintilimab (an immunotherapy that helps your immune system attack cancer), and nab-paclitaxel (a chemotherapy)—as the first treatment for triple negative breast cancer that has spread. The goal is to see if this combination is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
58 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are between 18 and 70 years old.
  • Your breast cancer is triple negative and has spread or come back.
  • You have not yet had any treatment for the cancer that has spread.
  • If you had chemotherapy before, it was at least 6 months before the cancer came back.
  • You are generally well enough to carry out daily activities (ECOG 0 or 1).
  • Your heart, liver, and kidney function are within acceptable levels.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07419880Not yet recruiting· Phase 2
Re-treatment with three drugs for stubborn triple negative breast cancer

This study tests a new combination of drugs—cromolyn, TQB2102, and panpulimab—for women with triple negative breast cancer that has not responded to previous immunotherapy. The goal is to see if this combination can shrink or slow the cancer and give you another treatment option.

Shanghai, Shanghai Municipality
NCT06538896Recruiting· Phase 2
Tislelizumab and nab-paclitaxel for advanced triple-negative breast cancer with bone spread

This trial tests a combination of two drugs, tislelizumab (an immunotherapy) and nab-paclitaxel (a chemotherapy), as the first treatment for advanced triple-negative breast cancer that has spread to the bones. It aims to see if this combination can help shrink or control the cancer.

Hangzhou, Zhejiang
NCT07601178Recruiting· Phase 2
Immunotherapy and targeted drugs for advanced triple-negative breast cancer

This trial tests a combination of four drugs—two immunotherapies (QL1706), an anti-angiogenic agent (anlotinib), and chemotherapy (nab-paclitaxel)—as a first-line treatment for advanced triple-negative breast cancer. The goal is to see if this combination slows or stops cancer growth better than standard treatment alone.

Nanjing, Jiangsu
NCT06849492Not yet recruiting· Phase 2
Genetic typing to guide first treatment for advanced triple-negative breast cancer

This study tests a new way to choose treatment for advanced triple-negative breast cancer, based on a special analysis of your tumor. The goal is to find a treatment that works better for your specific cancer type.

Shanghai, Shanghai Municipality
NCT06387628Recruiting· Phase 2
LM-108 with immunotherapy for advanced triple-negative breast cancer

This trial tests a new drug called LM-108 combined with a PD-1 inhibitor (a type of immunotherapy) for people with triple-negative breast cancer that has come back or spread. It aims to see if this combination can help shrink tumors or slow the disease.

Shanghai, Shanghai Municipality
NCT06786026Recruiting· Phase 2
Drug combo plus chemotherapy for first-line advanced triple-negative breast cancer

This trial tests whether adding an experimental immunotherapy drug (QL1706) with or without bevacizumab to standard chemotherapy can help people with advanced triple-negative breast cancer that hasn't been treated yet. It aims to improve outcomes for patients who have already had earlier treatment but whose cancer has come back or spread.

Shanghai, Shanghai Municipality

Hear when a new Breast Neoplasms trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.