Combined therapy before surgery for lymph node-positive esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial is testing a combination of chemotherapy and radiation (called total neoadjuvant therapy) before surgery for a type of esophageal cancer that has spread to lymph nodes. The goal is to see if this approach improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of esophageal cancer called adenocarcinoma that has spread to nearby lymph nodes.
- The cancer is stage T2 to T4a and has not spread to other organs.
- You are scheduled to receive either chemoradiation or a chemotherapy regimen called FLOT before surgery.
- You are 18 years or older, and if over 70, you will need a geriatric assessment.
- You have not had chemotherapy or radiation to the chest or belly area before.
- You are in generally good health with no serious heart or lung problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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