Bevacizumab and immunotherapy with radiation for melanoma brain metastases
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a combination of a drug that stops blood vessel growth (bevacizumab), immunotherapy, and focused radiation to treat melanoma that has spread to the brain and is causing symptoms. The goal is to see if this approach shrinks tumors and improves outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have melanoma that has spread to your brain and is causing symptoms (like headaches or weakness).
- You are able to have a type of targeted radiation called hypofractionated stereotactic radiotherapy.
- You are at least 18 years old.
- You have not had radiation to the brain before.
- Your lab test results (blood counts, kidney and liver function) meet safe levels.
- You can have an MRI of your brain and are willing to follow pregnancy prevention rules if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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