Clin2
NCT06194851Possibly a fitRecruiting

Oxytocin nasal spray plus couples therapy for Veterans with PTSD

Post-Traumatic Stress Disorder (PTSD)

Treatments studied

Part of Mental health clinical trials.

This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are a Veteran with a current PTSD diagnosis (symptoms lasting at least 3 months after the trauma).
  • You have an intimate partner (spouse or live-in partner for at least 6 months) who is willing to join the study.
  • You and your partner are not currently in other trauma-focused therapy or couples therapy during the study.
  • Neither you nor your partner has a current problem with alcohol or drugs that is not in recovery for at least 3 months.
  • No severe relationship violence or intimidation in the past year.
  • You must be able to attend virtual sessions with a private space and internet access.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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