Study on HPV after cone biopsy for cervical cancer
Part of Cancer, Women’s health & pregnancy clinical trials.
This study looks at women with early-stage cervical cancer (stage IB2) or a pre-cancer called AIS. The goal is to see if testing for HPV after a cone biopsy can help predict if the cancer will come back. Your HPV test results will be tracked over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have early-stage cervical cancer (stage IB2, tumor up to 4 cm) or a pre-cancerous condition called AIS (adenocarcinoma in situ).
- You are scheduled to have a cone biopsy (a small surgery to remove a cone-shaped piece of tissue from the cervix).
- You have had an HPV test before your cone biopsy.
- You are not pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how to sort people into higher- or lower-risk groups after abnormal HPV testing treatment (LEEP), using repeat HPV and Pap (cytology) tests. It may help improve follow-up plans by identifying who needs closer monitoring after LEEP.
This trial tests whether giving an HPV vaccine after a cone biopsy (a surgery to remove abnormal cells from the cervix) helps prevent the HPV-related disease from coming back. It may be an option for patients who have had treatment for cervical dysplasia and have not been vaccinated against HPV before.
This study looks at doing a diagnostic cervical conization (a cone-shaped tissue biopsy) when HPV remains persistent and there are warning signs, but initial pathology does not show precancer. It aims to find hidden precancer earlier or better understand HPV-related changes that were missed.
This study looks at whether monitoring HPV DNA in your blood after surgery can help predict if cervical cancer comes back, and whether this information can guide decisions about extra treatment. If you join, you'll provide blood samples before and after surgery to track your HPV levels.
This study follows women with an early abnormal cervix cell change (CIN2/CIN2-3) to see how HPV DNA “integration” relates to whether the condition improves or worsens. It may help doctors better predict prognosis and guide safer monitoring, especially if you want to become pregnant.
This study follows patients with cervical cancer caused by HPV (a common virus) who receive radiation and chemotherapy together. Researchers will track whether the HPV virus stays in the body after treatment and how this affects long-term outcomes.
Hear when a new Cervix Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.