Clin2
NCT06234072Possibly a fitNot yet recruiting

Astragalus plus gemcitabine before surgery for pancreatic cancer

Pancreatic Cancer

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests whether adding astragalus, an herbal supplement, to the standard chemotherapy drug gemcitabine before surgery can improve outcomes for people with pancreatic cancer. It is a phase 2 study designed to see if the combination is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with pancreatic ductal adenocarcinoma (a common type of pancreatic cancer).
  • You are 18 years or older.
  • You are in generally good health (able to care for yourself, up and about more than 50% of waking hours).
  • Your liver, kidney, and blood counts are within acceptable ranges as determined by tests.
  • The cancer has not spread to distant organs or the brain.
  • You have no other serious heart, HIV, or mental health conditions that would interfere.
  • You are willing to take herbal medicines (astragalus) and follow the treatment schedule.
  • If you are able to have children, you agree to use effective contraception during treatment and for 12 weeks after.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06177522Not yet recruiting· Phase 2
Immunotherapy and chemotherapy before surgery for pancreatic cancer

This trial tests a combination of an immunotherapy drug (adebrelimab) with chemotherapy before surgery for pancreatic cancer. The goal is to see if this approach can shrink the tumor and improve outcomes for patients whose cancer can be surgically removed.

Nanjing, Jiangsu
NCT07549958Recruiting· Phase 1
Gemcitabine with or without Pitavastatin for Advanced Pancreatic Cancer

This study tests whether adding pitavastatin (a cholesterol-lowering drug) to gemcitabine chemotherapy can help treat pancreatic cancer that cannot be surgically removed. You would join if your cancer hasn't grown worse after 2–4 rounds of gemcitabine.

Orange, California
NCT07131514Recruiting· Phase 2
Combination therapy for pancreatic cancer before and after surgery

This trial tests if giving a combination of four drugs before and after surgery can help treat pancreatic cancer. The drugs include HRS-4642, gemcitabine, nab-paclitaxel, and adebrelimab. It may help shrink the tumor before surgery and lower the chance of cancer coming back afterward.

Shanghai
NCT03498326Recruiting· Phase 2
Gemcitabine plus celecoxib after pancreatic surgery

This trial tests whether adding celecoxib to gemcitabine chemotherapy after complete (R0) pancreatic tumor removal can lower the chance the cancer comes back. It may help people who have had successful surgery but still need anti-cancer treatment.

Hangzhou, Zhejiang
NCT07108504Not yet recruiting· Phase 2
Targeted therapy combined with chemotherapy for advanced pancreatic cancer

This trial tests a new targeted drug (LM-302) combined with a standard chemotherapy drug (gemcitabine) for people with advanced pancreatic cancer that has progressed after initial treatment. The goal is to see if this combination can slow down or shrink the cancer.

NCT05903703Not yet recruiting
Canagliflozin plus chemotherapy for advanced pancreatic cancer

This trial tests whether adding the diabetes drug canagliflozin to a standard chemotherapy medicine (gemcitabine) can help treat advanced pancreatic cancer. The goal is to see if this combination can shrink tumors or improve survival.

Hangzhou, Zhejiang

Hear when a new Pancreatic cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.