Testing pirfenidone to prevent repeat pancreatitis attacks
Treatments studied
Part of Digestive system clinical trials.
This trial tests if pirfenidone, an anti-scarring drug, can reduce the number of repeat episodes of acute pancreatitis. You may be eligible if you've had two or more pancreatitis attacks at least three months apart and are not having an active attack right now.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 85 years old
- You have had at least two separate attacks of acute pancreatitis, with each attack diagnosed by belly pain, high pancreatic enzyme levels, and/or abnormal scans
- Your most recent pancreatitis attack ended at least 30 days ago, and you are now stable (no severe pain, vomiting, or fever)
- If a cause for your pancreatitis was found, you have treated it (e.g., had gallbladder removed, lowered triglycerides, stopped a problem medication)
- You are willing to take the study drug or placebo and follow the study schedule
- You do not have chronic pancreatitis, severe liver or heart disease, active cancer, or certain other medical conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether a procedure called ERCP can help find and treat the cause of recurrent pancreatitis that remains unexplained after standard tests.
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