Clin2
NCT05771675Possibly a fitRecruiting

Simvastatin trial for symptom relief in pancreatitis

Recurrent Acute PancreatitisChronic Pancreatitis

Treatments studied

Part of Digestive system clinical trials.

This early-phase study tests whether simvastatin can improve patient-reported symptoms in people with recurrent acute or chronic pancreatitis. It’s meant to see if the medicine is tolerable and helps with how you feel day to day.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
90 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • Be 18–75 years old and sign a consent form to join
  • Have recurrent acute or chronic pancreatitis that is not from gallstones or certain other causes (like autoimmune or medication-related)
  • Be able to take pills by mouth and agree to follow all study visits for the study duration
  • You must not have had any pancreatic surgery in the past
  • Do not use any statin medicines (including simvastatin) for at least 6 months before joining
  • If you could get pregnant: use very effective birth control during the study and for 1 month after the last dose (and not be pregnant)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06362187Not yet recruiting
VR pain relief study for chronic pancreatitis

This trial tests whether using virtual reality (VR) can help reduce abdominal pain in people with chronic pancreatitis. If you have ongoing pain from chronic pancreatitis, you may be able to join and try VR as a non-drug pain management option.

Los Angeles, California
NCT07755813Not yet recruiting· Phase 2
Pirfenidone for treating chronic pancreatitis pain

This trial tests whether pirfenidone, an oral medication that may reduce scarring and inflammation, can help relieve pain in people with chronic pancreatitis. If you have ongoing pain or frequent flare-ups, this study could offer a new treatment option.

NCT06253117Recruiting· Phase 2
Testing pirfenidone to prevent repeat pancreatitis attacks

This trial tests if pirfenidone, an anti-scarring drug, can reduce the number of repeat episodes of acute pancreatitis. You may be eligible if you've had two or more pancreatitis attacks at least three months apart and are not having an active attack right now.

Birmingham, Alabama
NCT06185621Recruiting
Aspirin to prevent recurrent pancreatitis

This trial tests if taking aspirin daily can prevent repeated attacks of acute pancreatitis. It's for people who have had at least two episodes of pancreatitis in the past year that were not caused by a medical procedure.

Xi'an, Shaanxi
NCT04647097Recruiting
Quit smoking and alcohol to prevent pancreatitis coming back

This trial is studying whether stopping alcohol and quitting smoking can help keep acute pancreatitis from returning. It’s for people whose pancreatitis happened because of alcohol, and who smoke every day.

Pécs
NCT05925036Recruiting· Phase 1
Cell therapy trial for pain from long-term pancreatitis

This Phase 1 study tests a new cell-based treatment to reduce pain caused by chronic pancreatitis. It’s designed mainly to check safety first, and it may help people with ongoing, opioid-stable pancreatic pain.

Charleston, South Carolina

Hear when a new Recurrent Acute Pancreatitis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.