Negative HIV test in children treated early: a study
Treatments studied
Part of Immune system & allergy, Infections clinical trials.
This study looks at why some HIV-positive children who started treatment early may have a negative HIV antibody test. It uses stored blood samples from children who were in the Pediacam III study to better understand the immune response.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must have been part of the earlier Pediacam III study.
- For the case group: your child had at least one negative HIV antibody test (ELISA) at some point, even if temporary.
- For the control groups: your child is HIV-positive with either low virus levels (under 400 copies/mL) or high virus levels (400 or more), OR your child is HIV-negative but born to an HIV-positive mother, OR your child is HIV-negative and born to an HIV-negative mother.
- Your child must have stored blood samples available from the Pediacam study.
- Your child's birth year must be between 2007 and 2010, and they must have been born full-term (37 weeks or later) or premature (under 37 weeks).
- If your child is HIV-positive and 11 years or older, they must understand their HIV status and agree to take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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