HIV vaccine study for infants born to mothers with HIV
Part of Immune system & allergy, Infections clinical trials.
This trial tests whether an experimental HIV vaccine, given with an adjuvant to boost the immune response, is safe and produces an immune response in infants who were exposed to HIV in the womb but are not infected. The study aims to help protect these vulnerable infants.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a mother living with HIV, at least 18 years old, and agree to take part with your baby.
- Your pregnancy is in the second or third trimester with one baby, and you plan to have a C-section at Chris Hani Baragwanath Hospital in Soweto.
- You have been on HIV medications (cART) for at least 16 weeks before delivery and your viral load is under 400 copies/mL near delivery.
- Your baby will be born by C-section at 37 weeks or later, weighs at least 5.5 pounds (2.5 kg), and is 7 days old or younger at enrollment.
- Your baby has certain blood test results (like hemoglobin, white blood cells, platelets) within healthy ranges and a negative HIV test at birth.
- Your baby has no serious birth defects or life-threatening illnesses and has started standard HIV prevention medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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