Maternal genes and Beckwith-Wiedemann syndrome risk study
Part of Genetic & congenital clinical trials.
This study looks at how a mother's genes and chemical changes to DNA (called epimutations) may increase the risk of having a child with Beckwith-Wiedemann syndrome or affect a woman's ability to get pregnant and carry a baby to term. It aims to find genetic clues that could help explain these reproductive challenges.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman under 35 years old (for Cohorts 2 and 3).
- You have a child with Beckwith-Wiedemann syndrome (Cohort 1).
- You are undergoing fertility treatment and have not had a live birth after three cycles or 6 embryos transferred (Cohort 2).
- You have had two or more pregnancy losses before 24 weeks of pregnancy (Cohort 3).
- You do not have other known causes of infertility or pregnancy loss (like ovarian disorders, hormone issues, or autoimmune conditions).
- You do not have chromosomal abnormalities found in standard genetic tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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