Virus plus immunotherapy and chemo before surgery for pancreatic cancer
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial tests giving a combination of an oncolytic virus, immunotherapy (PD-1 inhibitor), and chemotherapy before surgery to shrink pancreatic tumors and make them easier to remove. The goal is to improve outcomes for people with borderline resectable or locally advanced pancreatic cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have borderline resectable or locally advanced pancreatic cancer.
- You are in good general health (able to care for yourself, ECOG 0-1).
- You have not had chemotherapy, radiation, or immunotherapy for this cancer before.
- You have no other active cancers, serious infections, or uncontrolled medical conditions.
- You are not pregnant or breastfeeding and will use contraception if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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