Clin2
NCT06368934Worth exploringNot yet recruiting

Partial lobe removal for a certain type of brain tumor

GliomaGlioblastoma

Part of Cancer clinical trials.

This trial is testing whether removing only part of the brain lobe (sub-lobectomy) is effective for a certain type of aggressive brain tumor. It aims to see if this less extensive surgery can help patients with a specific genetic profile.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
326 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • You must have a newly diagnosed high-grade glioma (brain tumor) that has not been treated except with a biopsy.
  • You must be able to have an MRI with contrast.
  • You must be in good physical condition (KPS score of 70 or higher, meaning you can care for yourself).
  • The tumor must be in a single lobe of the brain (front, side, or back) and can be completely removed by surgery.
  • Your tumor must have specific genetic changes (IDH wild-type and TERT promoter mutation) that must be confirmed during surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06623565Recruiting
Advanced imaging for extensive brain tumor removal

This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.

Amsterdam, North Holland
NCT06176066Recruiting· Phase 1
MRI-guided surgery for glioblastoma

This trial is testing a new way to find and remove glioblastoma brain tumors using a special MRI scan. It may help doctors remove more of the tumor safely during surgery.

Los Angeles, California
NCT07218367Not yet recruiting· Phase 1
Study of new imaging before brain surgery for glioblastoma

This trial looks at a new imaging method to help doctors see brain tumors more clearly before surgery. It may help remove the tumor more safely and completely.

West Los Angeles, California
NCT06118723Recruiting
Supramaximal vs maximal surgery for brain tumors

This trial compares removing as much tumor as safely possible (supramaximal resection) with standard maximal resection in people with high-grade glioma (an aggressive brain tumor). The goal is to see if more extensive removal improves survival and quality of life.

San Francisco, California
NCT06146725Recruiting
Resection vs. biopsy in high-grade glioma patients

This study compares whether having surgery to remove as much of the tumor as possible (resection) or just taking a small sample (biopsy) leads to better outcomes for people with a fast-growing brain tumor (high-grade glioma). The goal is to help guide treatment decisions.

San Francisco, California
NCT05386043Recruiting
Study brain tumor testing with MRI and extra tissue samples

This study looks at how brain tumors look on MRI and what biopsy tissue shows, using samples taken during planned surgery. It may help improve understanding of tumor biology and future treatment planning.

Indianapolis, Indiana

Hear when a new Glioma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.