Clin2
NCT06389123Worth exploringRecruiting

Targeted radiation for metastatic cancer that stopped responding

Metastatic Cancer

Treatments studied

Part of Cancer clinical trials.

This study tests a new approach that first uses a special scan to find cancer cells that have a specific marker, then delivers targeted radiation to those cells. It is designed for people with advanced solid tumors that have spread and stopped responding to standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 or older and able to understand what the study involves.
  • Your cancer must have spread to other parts of the body (metastatic), and you must have at least one tumor that can be measured on a scan.
  • You must have tried at least one standard treatment that stopped working or wasn't effective.
  • You need to be in reasonably good health overall, able to do light activities (score of 2 or less on a performance scale), and expected to live at least 3 more months.
  • You must have a recent tumor sample (biopsy) available from your cancer, preferably from a site where it spread.
  • You cannot have certain bleeding conditions, uncontrolled infections, severe heart failure, or be pregnant or breastfeeding.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06228482Recruiting· Phase 1
Targeted radioactive therapy for advanced lung cancer

This trial tests a new targeted radioactive drug that seeks out a specific marker on lung cancer cells. It first uses a low-dose imaging scan to see if the cancer cells have this marker, then gives a higher-dose treatment to destroy those cells.

Sacramento, California
NCT07020806Recruiting· Phase 1
New imaging test for invasive lobular breast cancer that has spread

This trial tests a new imaging agent, [68Ga]Ga DOTA-5G, to see if it can better detect invasive lobular breast cancer that has spread to other parts of the body. It involves a PET/CT scan and may help doctors understand the extent of your cancer.

Sacramento, California
NCT07608848Recruiting· Early Phase 1
Imaging study of new cancer-targeting radioactive drugs

This study tests two new radioactive drugs designed to find and image advanced breast or prostate cancer. The drugs use special imaging scans (PET and SPECT) to locate tumors and may help guide future treatment decisions.

Perth, Western Australia
NCT04939610Recruiting· Phase 1/Phase 2
Studying a targeted radiation drug for advanced solid tumors

This trial tests how safe and effective a targeted radiation medicine (177Lu-FAP-2286) is for people with advanced solid cancers that have limited treatment options. It may help by delivering radiation directly to cancer-related targets and shrinking tumors.

Birmingham, Alabama
NCT04529044Recruiting· Phase 2
177Lu-DOTATATE for advanced breast cancer with targeted receptors

This Phase 2 trial tests whether 177Lu-DOTATATE can slow or shrink stage IV or recurrent breast cancer. It targets tumor “receptors” found on scans, using a radioactive medicine that delivers radiation directly to cancer cells.

Portland, Oregon
NCT06611891Recruiting· Phase 3
PET scan study for breast cancer with hormone receptors

This study tests a special PET scan called 68Ga-DOTATOC to see if it can find certain breast cancer cells in the body. It may help doctors better understand your cancer, especially if it has spread to the liver or bones.

Grenoble

Hear when a new Metastatic Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.