Clin2
NCT06391125Possibly a fitRecruiting

Lidocaine for pain relief with penicillin shot for syphilis

Syphilis InfectionBenzathine Penicillin Adverse Reaction

Treatments studied

Part of Infections clinical trials.

This study tests if adding a numbing medicine (lidocaine) to a penicillin shot reduces the pain of the injection for people being treated for syphilis. If you are starting your first of three weekly penicillin shots, you may be able to join.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have confirmed syphilis (positive blood test).
  • This is your first injection of penicillin for this syphilis episode (if you need three weekly shots).
  • You are not allergic to penicillin or lidocaine.
  • You are not pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people

This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.

Lancaster, California
NCT07418021Not yet recruiting
Cold spray and buzzy device for penicillin shot pain

This study tests whether a cold spray or a vibrating device (called Buzzy) can help reduce pain and fear when getting a penicillin shot. If you're scheduled for one, these methods might make the experience more comfortable.

NCT07189208Recruiting· Phase 2
Preventing syphilis during pregnancy

This study tests whether taking an antibiotic (penicillin) during pregnancy can prevent syphilis infection in women who are at higher risk. If you are pregnant and have certain risk factors, this trial may help keep you and your baby safe from syphilis.

Duque de Caxias, Rio de Janeiro
NCT06069141Recruiting
Comparing syphilis treatments for people with HIV

This study compares the standard treatment for early syphilis with a combination that includes an extra antibiotic, to see which is more effective. It is for people living with HIV who have early syphilis.

Hsinchu, Taiwan
NCT07048769Recruiting· Phase 4
Pain relief shot for saline ultrasound of the uterus

This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.

Hartsdale, New York
NCT06921213Recruiting· Phase 2
Oral antibiotics for newborns exposed to syphilis

This study tests whether giving oral antibiotics at home is as safe and effective as the usual injections for newborns exposed to syphilis during pregnancy. It is for babies who appear healthy at birth.

Jakarta

Hear when a new Syphilis Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.