TIP chemo plus triplizumab before surgery for penile cancer
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a combination of chemotherapy drugs (paclitaxel, ifosfamide, cisplatin) and an immunotherapy drug (triplizumab) given before surgery for locally advanced penile cancer. The goal is to shrink the tumor and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have squamous cell carcinoma of the penis confirmed by a biopsy or other test.
- Your cancer should be locally advanced (stage T4 or N3).
- You cannot have had chemotherapy for this cancer in the last 12 months.
- You must have at least one tumor that can be measured on a scan (like a CT or MRI).
- You should be in fairly good health, able to walk and take care of yourself (ECOG score 0-2).
- Your blood counts, liver, and kidney function must be within certain ranges.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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