Chemo plus immunotherapy for advanced penile cancer
Treatments studied
Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests a combination of two chemotherapy drugs (carboplatin and paclitaxel) plus the immunotherapy drug pembrolizumab (Keytruda) for penile cancer that has spread to nearby lymph nodes. The goal is to see if this combination can shrink or control the cancer before or after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have squamous cell carcinoma of the penis (a specific type of penile cancer).
- Your cancer has spread to lymph nodes in the groin or pelvis, or you have a lymph node that came back after previous treatment.
- You must be well enough to be up and about (ECOG score 0 or 1).
- You cannot have had prior treatment with a checkpoint inhibitor (like Keytruda).
- You must be able to provide a tumor tissue sample (biopsy) for testing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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