Doxycycline to prevent infection after dental procedures
Treatments studied
Part of Heart & circulation, Infections clinical trials.
This trial tests whether taking doxycycline before a dental extraction can prevent bacteria from entering the bloodstream. It might help people who need teeth pulled under general anesthesia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have at least 10 teeth.
- You need a tooth pulled under general anesthesia (for behavioral reasons).
- You are 18 years or older and weigh at least 40 kg (about 88 pounds).
- You have not taken antibiotics in the last 3 months.
- You do not regularly use mouthwash or other oral antiseptics.
- You do not have a history of allergy to doxycycline or clindamycin.
- You do not have any immune problem, risk for heart infection, or risk for heavy bleeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at ways to lower the risk of infective endocarditis, a serious heart infection that can happen after certain bacteria enter the bloodstream from the mouth. You may be asked to pause routine dental cleanings for a period while they track dental health and infection risk.
This study checks whether giving a preventive antibiotic (before certain dental procedures) can lower the risk of heart infection in people with prosthetic heart valves or a past heart infection. You may be included if you need an invasive dental procedure and meet timing and history requirements.
This trial tests if a common antibiotic (azithromycin) can help treat infection and bone loss around dental implants without surgery. If you have an implant with deep pockets and bone loss, this study might offer a non-surgical treatment option.
This study looks at whether giving antibiotics after a tooth extraction helps reduce the risk of infection. It is for healthy adults between 18 and 50 who are having a tooth removed.
This study tests if clindamycin, a common antibiotic, works as well as vancomycin to prevent infections during heart surgery on the aorta (the main artery from the heart). Patients must be having planned morning surgery with the heart-lung machine and understand French.
This trial tests whether taking antibiotics before a bone graft procedure helps prevent infection better than a placebo. If you need a tooth pulled and a bone graft, you may be able to join.
Hear when a new Bacteremia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.