Antibiotics before fecal transplant for chronic constipation
Part of Digestive system clinical trials.
This study tests whether giving antibiotics before a fecal microbiota transplant (a procedure that delivers healthy donor stool into your colon) improves treatment for chronic constipation. You will need to stop certain medications and undergo a colonoscopy-based procedure, with close follow-up.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have had chronic constipation for at least 6 months, with fewer than 3 spontaneous bowel movements per week and hard or lumpy stools (Bristol types 1 or 2) at least 25% of the time.
- You cannot have a physical blockage in your gut (like a prolapse or narrowing from disease) or constipation caused by other conditions like Parkinson's, diabetes, or opioid use.
- You must not have had abdominal or pelvic surgery (except for cesarean, appendix removal without complications, or treated polyps).)
- You must not have taken antibiotics, antifungals, or antivirals in the last 14 days, and you must be able to stop certain medications that affect gut motility or the microbiome during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a treatment that puts healthy bacteria into your gut along with prebiotics (food for good bacteria) to help with long-lasting constipation that hasn't improved with other treatments.
This trial tests if a fecal microbiota transplant combined with nutritional support can improve chronic constipation that hasn't gotten better with standard treatments. It's a small early study to see if the approach is safe and works.
This study tests whether taking antibiotics before a fecal microbiota transplant (WMT) improves IBS symptoms. It compares how well the transplant works when patients have antibiotics beforehand versus not.
This study tests a special treatment called washed microbiota transplantation for chronic constipation. It uses healthy donor bacteria to help improve your bowel movements.
This trial tests a treatment called washed microbiota transplantation (a procedure that delivers healthy gut bacteria to your colon) for adults with chronic constipation. The goal is to see if it can improve bowel movements without the need for laxatives.
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
Hear when a new Chronic Constipation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.