Does THC and CBD help severe itching?
Treatments studied
Part of Skin clinical trials.
This study tests whether a combination of two cannabis-based compounds (THC and CBD) can safely relieve severe itching that hasn't gotten better with other treatments. You'll either receive the active treatment or a placebo for several weeks, and neither you nor your doctor will know which one you're getting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your itch is severe — on a 0–10 scale, it's a 7 or higher over the past week.
- You have tried other treatments for your itch, and they either didn't help enough or caused side effects.
- You are willing to keep your current itch treatment the same for at least 6 weeks during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether combining hypnosis with virtual reality can reduce chronic itch. It may help if you have had itching for at least a year, seen a doctor for it, and it still affects your daily life despite treatment.
This trial tests a special light treatment (photobiomodulation) to see if it can safely reduce itch. It compares the treated area to a similar untreated area on your body.
This Phase 3 study tests whether dupilumab injections can reduce severe itching that has no clear cause. It also checks how safe the medicine is over the study period.
This study tests a cannabis-based cream on eczema-related itch over 4 weeks. It may help reduce itching if other treatments haven't worked, but requires pausing other skin products during the trial.
This study tests if applying several itch-causing substances at once makes you itch more. It is for healthy adults who want to help researchers understand itch better.
This study looks at how a placebo might help reduce two kinds of itch: one caused by histamine (like an allergy) and another caused by other substances. You will receive different creams or patches to test how your body responds.
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