Clinical trials
Pruritus clinical trials
Below are recruiting pruritus clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06790537RecruitingPhase 4
Pregabalin for itching in diabetes: a controlled study
This trial tests if pregabalin can reduce chronic itching in people with type 2 diabetes. It compares pregabalin against a placebo (inactive pill) to see if itching improves more with the active drug.
Chandigarh, ChandigarhAges 18 years+ - NCT05678309Recruiting
Study to create a patient library for itch without a cause
This trial sets up a patient library for people who have itching with no clear underlying skin or medical cause. It aims to collect patient input and experiences to improve understanding and support for this condition.
BrestAges 18–99 - NCT07560618RecruitingPhase 4
Testing a new cream for itch relief in atopic dermatitis
This study tests whether roflumilast cream (a new anti-inflammatory medication applied to the skin) can reduce the intense itching caused by atopic dermatitis (eczema). You'll track your itching daily using a smartphone app and visit the clinic to see if the cream helps over time.
Sacramento, CaliforniaAges 12 years+ - NCT07098351Recruiting
A trial for a new itchy skin medicine for people on peritoneal dialysis
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
Guangzhou, GuangdongAges 18–85 - NCT06297499RecruitingPhase 1
Testing ondansetron to prevent itching after C-section
This trial tests if giving ondansetron before spinal anesthesia can prevent itching that often happens after a C-section. It may help you feel more comfortable during recovery.
Detroit, MichiganAges 18–50 - NCT07312916Recruiting
Hand massage for itching in kidney dialysis patients
This study tests whether hand massage can help reduce the chronic itching that many people on dialysis experience. It compares two groups to see if massage provides relief and improves quality of life.
Lausanne, Canton of VaudAges 18 years+ - NCT06506240Recruiting
Acupuncture for itching in older adults
This trial tests if acupuncture can reduce chronic itching in people aged 60–80. It may help if you have moderate to severe itching without serious skin damage or other major health issues.
Beijing, Beijing MunicipalityAges 60–80 - NCT07054775RecruitingPhase 4
Comparing itching after two doses of spinal morphine in C-section
This study compares two low doses of morphine given during spinal anesthesia for planned cesarean sections, to see which causes less itching. It aims to find a safer way to manage pain after birth.
Khon KaenAges 18–45 - NCT05689463Recruiting
Testing antibodies in itching after immune therapy
This study checks blood antibodies (BP180 and BP230) in people who develop long-lasting itching after starting immune therapy for cancer. It may help doctors understand why the itching happens and how it relates to autoimmune skin conditions.
RouenAges 18 years+ - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT05263206RecruitingPhase 3
Shot medicine (dupilumab) for severe, unexplained chronic itching
This Phase 3 study tests whether dupilumab injections can reduce severe itching that has no clear cause. It also checks how safe the medicine is over the study period.
Bakersfield, CaliforniaAges 18–90 - NCT06748404RecruitingPhase 2
TriCalm Hydrogel for Itching from Immunotherapy
This trial tests a gel called TriCalm Hydrogel to see if it helps reduce itching caused by immunotherapy cancer treatment. If you have itching from your immunotherapy, this study might offer relief.
La Jolla, CaliforniaAges 18 years+ - NCT06994520Enrolling by invitationPhase 2
Topical cannabis extract for eczema itch
This study tests a cannabis-based cream on eczema-related itch over 4 weeks. It may help reduce itching if other treatments haven't worked, but requires pausing other skin products during the trial.
Khon Kaen, Changwat Khon KaenAges 25 years+ - NCT05042258RecruitingPhase 4
Dupilumab to improve sleep and itch in children with eczema
This trial studies whether dupilumab can improve daily body clock (circadian function), sleep, and itching in children with moderate-to-severe eczema that isn’t well controlled by creams. It may help kids who are having significant sleep trouble and ongoing itch.
Chicago, IllinoisAges 6–17 - NCT05500794Recruiting
Meditation for itch from psoriasis or eczema
This trial studies whether meditation can reduce itching and improve quality of life in adults with plaque psoriasis or atopic dermatitis (eczema). It may help by calming the mind and reducing discomfort related to inflammatory skin disease.
ParisAges 3 weeks+ - NCT06120907Recruiting
Swiss Itch Registry: Tracking chronic itch
This study is a registry, which means it collects information about people with chronic itching. By joining, you help researchers learn more about different causes and treatments of chronic itch, with no extra tests or medicines.
BaselAges 14 years+ - NCT06226610RecruitingPhase 2
Testing dupilumab for severe itching after burn injuries
This trial tests if dupilumab (Dupixent) can help adults with long-lasting, severe itching from healed burn scars. It is for people whose itching has not improved with standard treatments like antihistamines.
Akron, OhioAges 18–60 - NCT06446609Recruiting
Itching in drug-induced liver injury study
This study looks at itching caused by drug-induced liver injury. Researchers want to understand who gets itchy and how bad it is, which could help improve care for people with this condition.
NottinghamAges 18 years+ - NCT06488742Recruiting
Kanuka oil vs. hydrocortisone for eczema
This trial tests if a cream made from kanuka oil works better than a mild steroid cream (hydrocortisone) to treat eczema. It looks at how much the itching and skin rash improve.
Boynton Beach, FloridaAges 12–75 - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT06751056Recruiting
Neck traction to reduce itch medication use
This study tests if a gentle neck stretch (cervical traction) can help people with chronic itch on the scalp, arms, or upper back take less gabapentin or pregabalin (medicines for nerve-related itch). If you have had a stable dose of these medicines for at least four weeks and don't have a skin rash causing the itch, this trial may offer a drug-free way to manage your symptoms.
Scottsdale, ArizonaAges 18 years+ - NCT06787794Recruiting
Itch relief using hypnosis and virtual reality
This trial tests whether combining hypnosis with virtual reality can reduce chronic itch. It may help if you have had itching for at least a year, seen a doctor for it, and it still affects your daily life despite treatment.
Leiden, South HollandAges 18–80 - NCT07245238RecruitingPhase 3
CBD lotion for itching in scleroderma
This trial tests if a CBD (cannabidiol) lotion can help reduce itching in people with scleroderma, a condition that often causes chronic itch. It compares the CBD lotion to a placebo (inactive lotion) to see if it works and is safe.
Khon KaenAges 18–70 - NCT07259343Recruiting
Cream with milk peptide for children's mild eczema
This trial tests if a special cream made with a milk protein peptide can improve mild eczema symptoms like itching and reduce bacteria on the skin in children aged 2 to 12.
Aguascalientes, AguascalientesAges 2–12
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Common questions
- Are there clinical trials for pruritus?
- Yes. Clin2 currently lists 26 recruiting pruritus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pruritus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pruritus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.