Guiding colorectal cancer treatment with a blood test after initial chemo
Part of Cancer, Digestive system clinical trials.
This trial tests whether adjusting treatment based on a simple blood test (circulating tumor DNA) after two cycles of chemo can be safe and effective for people with advanced colorectal cancer. The goal is to tailor therapy to each person's response.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your colorectal cancer must be left-sided or in the rectum, not right-sided.
- The tumor must be microsatellite stable (MSS) and not have a BRAF V600E mutation.
- You must not have had chemotherapy for metastatic disease before.
- You must be at least 18 years old and in generally good health (ECOG 0 or 1).
- Your blood counts, liver and kidney function must be within acceptable limits.
- You cannot have certain conditions like serious heart problems, active infections, or recent major surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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