Personalized treatment for advanced breast cancer using lab-grown tumor models
Part of Cancer, Skin clinical trials.
This trial tests a personalized approach to cancer treatment. Doctors will grow a ‘mini-tumor’ from a biopsy of your cancer in the lab to help find the best therapy for you. It is for people with advanced breast cancer that has not responded well to standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have advanced breast cancer that is either triple-negative (HR-/HER2-), or hormone-positive/HER2-negative that has stopped responding to hormone therapy and CDK4/6 inhibitors.
- Your tumor must be measurable on scans and accessible for a biopsy (a small sample taken from the tumor).
- You must be in good enough health to be up and around (performance status 0 or 1).
- You cannot have had more than 3 different chemotherapy treatments for advanced breast cancer (hormone therapy and CDK4/6 inhibitors are not counted in this limit).
- You cannot have brain metastases that are getting worse or spread to the lining of the brain and spinal cord (leptomeningeal disease).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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