Prebiotic diet to boost immunotherapy for melanoma
Part of Cancer clinical trials.
This trial tests whether a special prebiotic diet can help your body's bacteria (microbiome) better respond to standard immunotherapy for advanced melanoma that cannot be removed by surgery. If you are starting your first immunotherapy, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and speak English.
- You have advanced melanoma (stage III or IV) that cannot be removed by surgery, and you are about to start your first immunotherapy treatment.
- You are willing to eat study-provided foods (which can be tailored to your taste) and follow the study schedule, including blood and stool samples.
- You have not had immunotherapy before for metastatic melanoma, and you do not have certain intestinal conditions like Crohn's disease or a history of bariatric surgery.
- You are not currently taking high-dose steroids, using antibiotics, or smoking heavily, and you are not pregnant or planning to become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if eating certain prebiotic foods while receiving immunotherapy before melanoma surgery can boost your immune system and improve treatment response. Participants eat study-provided foods and receive standard immunotherapy (ipilimumab with or without nivolumab, or nivolumab with or without relatlimab).
This trial tests whether adding a postbiotic (a gut-health supplement) to a standard immunotherapy called anti-PD-1 makes it work better for people with advanced melanoma that hasn't been treated yet. It may help shrink tumors or slow the cancer's growth.
This trial tests if adding extra dietary fiber before and during immunotherapy can change gut bacteria to make the treatment more effective. It is for people with advanced melanoma who are about to start their first immunotherapy.
This trial studies whether eating a high-fiber diet can improve how well immunotherapy works against melanoma by affecting gut bacteria. If you have melanoma and are starting or have recently started immunotherapy, this study may be relevant.
This study tests whether a change in diet can help people with early-stage melanoma or lung cancer who are receiving immunotherapy (a type of treatment that helps your immune system fight cancer). You will be asked to follow a diet, give blood and stool samples, and complete questionnaires to see how the diet affects your body and treatment.
This trial tests whether a special diet low in certain amino acids (building blocks of protein), combined with an immune-boosting antibody drug, can safely shrink stage III melanoma that has spread to lymph nodes. The goal is to see if this combination works better than standard treatment.
Hear when a new Unresectable Melanoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.