Different radiotherapy doses with immunotherapy for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests different doses of radiation therapy combined with an immunotherapy drug called sintilimab for people with advanced esophageal cancer that hasn't spread far. The goal is to find the best dose to shrink tumors and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a type of esophageal cancer called squamous cell carcinoma that has spread locally but not to distant organs.
- You have at least one tumor that can be measured on scans.
- You are in good enough health to be up and about (able to do light work or daily activities).
- Your organs (like liver, kidneys, bone marrow) are working well enough.
- You have not had any prior cancer treatment like chemotherapy, radiation, immunotherapy, or certain traditional Chinese medicines for this cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a short course of radiation combined with the immunotherapy drug Sintilimab before surgery for esophageal cancer. The goal is to see if this combination makes the tumor shrink more and improves treatment results.
This Phase 3 trial studies whether adding sintilimab (an immunotherapy medicine) after surgery improves outcomes for people with locally advanced esophageal squamous cell carcinoma. It compares sintilimab plus a chemo/RT plan versus the same chemo/RT plan without immunotherapy.
This study tests a combination of an immunotherapy drug (sintilimab) with chemotherapy given before surgery for a type of esophageal cancer called squamous cell carcinoma. The goal is to see if this treatment shrinks the tumor and improves outcomes.
This trial tests giving the immunotherapy drug sintilimab together with chemotherapy before and after surgery for esophageal squamous cell carcinoma. It aims to see if this combination can help improve outcomes for patients whose tumors can be surgically removed.
This trial tests whether giving the immunotherapy drug sintilimab together with standard chemotherapy and a growth factor injection before surgery can help people with a certain type of esophageal cancer (squamous cell carcinoma) that is still removable. The goal is to improve treatment outcomes before the operation.
This trial looks at adding sintilimab (an immunotherapy) after surgery for certain stages of esophageal squamous cell cancer. The goal is to lower the chance the cancer comes back after standard treatment.
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