Short radiation before surgery with an immunotherapy drug for esophageal cancer
Part of Cancer, Digestive system clinical trials.
This trial tests a short course of radiation combined with an immunotherapy drug called sintilimab before surgery for esophageal squamous cell carcinoma. The goal is to see if this combination can shrink the tumor and improve treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with esophageal squamous cell carcinoma (a type of esophageal cancer) that can be removed with surgery.
- Your cancer has reached a certain stage (T3-4 or N+), meaning it has grown into deeper layers or spread to nearby lymph nodes.
- You are in good overall health (able to do daily activities with minimal help).
- You have not had any prior treatment for this cancer, including radiation, chemotherapy, immunotherapy, or traditional Chinese medicine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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