Clin2
NCT06470841Possibly a fitNot yet recruiting

CHG with venetoclax and azacytidine for new AML

Acute Myeloid Leukemia

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a combination of three drugs (CHG, venetoclax, and azacytidine) for people with newly diagnosed AML who haven't had treatment yet. It aims to see how well this combination works and if it is safe.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
85 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have been diagnosed with acute myeloid leukemia (AML) according to standard WHO criteria.
  • You must not have received any prior treatment for AML.
  • You must not have an active or uncontrolled infection within 14 days of starting the trial.
  • You must not have severe or unstable heart, liver, kidney, or metabolic disease that requires treatment.
  • If you are pregnant or breastfeeding, you cannot join this trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06386302Recruiting
Chidamide, venetoclax, and azacitidine for new AML

This trial tests a combination of three oral medications (chidamide, venetoclax, and azacitidine) for people newly diagnosed with acute myeloid leukemia (AML) who cannot receive strong chemotherapy. The goal is to see if this gentler treatment can work well with fewer side effects.

Tianjin, Tianjin Municipality
NCT06928376Recruiting· Phase 2
Venetoclax plus chemo vs standard chemo for AML

This trial tests a new combination of venetoclax plus a chemotherapy regimen (called CACAG) against a standard chemotherapy regimen (3+7) for adults with newly diagnosed intermediate- or high-risk AML. The goal is to see if the new combination works better.

Beijing, Beijing Municipality
NCT06451861Recruiting· Phase 2
Testing a new drug combo for newly diagnosed AML

This trial tests a new combination of drugs (ABC-14) against the standard treatment for adults newly diagnosed with acute myeloid leukemia (AML) who haven't had intensive treatment yet. The goal is to see if the new combo works better and is safe.

Dongguan, Guangdong
NCT07044687Recruiting· Phase 4
Venetoclax with azacitidine for newly diagnosed AML

This trial tests a combination of oral venetoclax and injected azacitidine for adults who are newly diagnosed with acute myeloid leukemia (AML) and cannot have standard strong chemotherapy. The goal is to see how well this treatment works and what side effects it may cause.

Gurgaon, Haryana
NCT06697327Enrolling by invitation
Testing a three-drug combo for newly diagnosed AML

This trial tests a combination of three drugs—daunorubicin, cytarabine, and venetoclax—for people with newly diagnosed AML who are strong enough to receive intensive chemotherapy. The goal is to see if adding venetoclax helps improve treatment outcomes.

Hefei, Anhui
NCT05805098Recruiting· Phase 2/Phase 3
Testing Venetoclax with chemo for newly diagnosed AML

This trial studies whether adding venetoclax to standard induction chemotherapy (homoharringtonine plus cytarabine) can improve outcomes for people with newly diagnosed AML. It mainly looks at people who can safely receive intensive chemotherapy but have certain heart, kidney, or lung limits.

Suzhou, Jiangsu

Hear when a new Acute Myeloid Leukemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.