Cervical numbing injection before laminaria placement
Part of Women’s health & pregnancy clinical trials.
This study tests a numbing injection into the cervix (the lower part of the uterus) before placing laminaria, thin rods that help open the cervix for a procedure called dilation and evacuation. The goal is to see if this reduces pain during the placement.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your pregnancy termination must be approved by a medical committee, or you must be experiencing a missed abortion (when the pregnancy has stopped but has not passed).
- You must be between 18.0 and 22.5 weeks pregnant (based on how far along you are).
- You can only be pregnant with one baby (not twins or more).
- You cannot have had a prior cesarean section (C-section).
- You cannot be allergic to lidocaine (a numbing medication).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether combining two medications (lidocaine and ketorolac) given as a shot around the cervix can help with pain when placing small sticks (dilators) to prepare for an abortion procedure. If you are 16–24 weeks pregnant and planning an abortion, this trial may help you feel less discomfort.
This study tests using a small balloon to prepare the cervix for a same-day abortion procedure between 18 and almost 20 weeks of pregnancy. It may help people who want the procedure done without needing to stay overnight.
This study compares two methods of preparing the cervix (the opening to the uterus) on the same day as a dilation and evacuation (D&E) procedure for abortion at 16 to 18 weeks of pregnancy. The goal is to see which preparation approach works best and is safest.
This study tests whether using a special balloon catheter to prepare the cervix before a dilation and evacuation (D&E) procedure works well. It might help make the procedure safer and easier for people who choose to end a pregnancy in the second trimester.
This study tests if using lidocaine gel on the cervix before placing a ripening balloon can reduce pain for pregnant women at full term. It may help women who want this balloon to start labor feel more comfortable.
This Phase 3 study tests whether a preventive numbing medicine injection before a vaginal hysterectomy (using the vNOTES approach) can reduce pain afterward. It may help with comfort and recovery after surgery for non-cancer reasons.
Hear when a new Dilation and Evacuation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.