Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are expected to need a breathing machine (ventilator) for more than 24 hours, and you have already started calming medicine.
- You have been on the breathing machine and sedated for no more than 12 hours before arriving in the ICU.
- You do not regularly take strong painkillers like morphine or fentanyl.
- You do not have severe liver or kidney failure, serious brain injury, or a known allergy to morphine or fentanyl.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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