Treatment
Fentanyl clinical trials
We’re tracking 60 recruiting studies that include Fentanyl, each written for real people, not researchers, below.
Recruiting studies
- NCT07276867Recruiting
Spinal Add-On Medicine for Leg Amputation from Sarcoma
This trial tests adding two medicines (dexmedetomidine and fentanyl) versus fentanyl alone to the standard spinal anesthetic for above-knee amputation surgery for lower limb sarcoma. The goal is to see if the combination provides better pain control during and after surgery.
CairoAges 18–60 - NCT07459166RecruitingPhase 2
Testing a new drug for fentanyl overdose
This study tests a new drug, CS-1103, to see if it can safely help reverse the effects of fentanyl (a strong opioid) even after a naloxone block. Healthy volunteers who have used opioids before will be given fentanyl and then the study drug, while researchers monitor safety and how the drug works.
Glendale, CaliforniaAges 18–55 - NCT07190625RecruitingEarly Phase 1
Fentanyl spray versus injection for pain in preterm babies
This trial compares giving fentanyl as a nasal spray versus an injection to help preterm babies during painful procedures like placing a central line, inserting a breathing tube, or a spinal tap. The goal is to see which method works better and is safer.
CairoAges Up to 4 weeks - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT06561672Enrolling by invitationEarly Phase 1
Pain relief study for day surgery patients
This study tests if a combination of paracetamol and tramadol works as well as fentanyl for preventing pain after day surgeries. The goal is to help patients recover faster with fewer side effects.
Zagazig, Sharqia ProvinceAges 21–65 - NCT07141589Recruiting
Comparing pain relievers added to numbing for eye surgery
This study compares two medicines (fentanyl and ketorolac) added to the numbing injection used during eye surgery. The goal is to see which one works better to reduce pain and make the surgery more comfortable.
CairoAges 18 years+ - NCT07640516Recruiting
Pain Relief Comparison for Amputation Surgery in High-Risk Patients
This study compares two medications (dexmedetomidine and fentanyl) mixed with a numbing agent to see which works better for blocking pain during above-knee amputation surgery in patients with serious heart or lung disease. Both drugs are already used in anesthesia, and this trial tests which combination is safest and most effective for you.
CairoAges 18 years+ - NCT06051227RecruitingPhase 3
Pain relief after injury: fentanyl vs. esketamine
This trial compares two strong pain medicines—fentanyl and esketamine—to see which works better for treating pain right after a traumatic injury. You would receive the medicine by spray in your nose or through a vein before going to the hospital.
AmsterdamAges 18 years+ - NCT06281951RecruitingPhase 1
Nebulized fentanyl study in healthy volunteers
This trial tests a nebulized (inhaled mist) form of fentanyl in healthy volunteers to see how it works in the body. It is a first-in-human study of the drug given through a nebulizer, which might help people with acute pain in the future.
Rouen, FranceAges 18–68 - NCT06953453RecruitingPhase 1
Inhaled fentanyl for cancer patients
This study tests an inhaled fentanyl spray for pain relief in Chinese adults with solid tumors. You may join if you have stable blood counts and organ function, and have not used strong painkillers recently.
Zhengzhou, HenanAges 18–55 - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT07076368RecruitingPhase 3
Ropivacaine and Fentanyl for Labor Pain Relief
This study tests two common pain medicines, ropivacaine and fentanyl, for women in labor who request an epidural. It aims to understand the best way to start labor pain relief with an epidural.
San Francisco, CaliforniaAges 18 years+ - NCT06642649Recruiting
Comparing anesthesia types to reduce opioids in hysterectomy
This study compares general anesthesia alone to two types of combined anesthesia (general plus spinal) to see which reduces the amount of opioid painkillers needed during and after a laparoscopic hysterectomy. It may help patients recover with less reliance on strong pain medications.
Bellinzona, SwitzerlandAges 18 years+ - NCT07435337RecruitingPhase 4
Pain medicine study for heart surgery patients
This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07657897Recruiting
Anesthesia effects on inflammation in liver cancer treatment
This study looks at how different types of anesthesia or sedation affect inflammation in people with early-stage liver cancer who are having a procedure called radiofrequency ablation (RFA). RFA uses heat to destroy small tumors, and researchers want to see if the choice of anesthesia influences the body's immune response, which might help improve recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07697404RecruitingPhase 4
Finding the best dose of ciprofol for children's breathing mask
This study tests a new sedative medicine (ciprofol) to find the best dose for placing a breathing tube mask in children during surgery. It may help your child get a safer, more comfortable experience.
Wuhan, HubeiAges 1–12 - NCT05150795RecruitingEarly Phase 1
Testing pregabalin before surgery versus fentanyl during surgery
This trial compares two medicines used around the time of surgery—pregabalin given by mouth before surgery versus fentanyl given during surgery—to see which better controls pain after the operation. You might join if you’re a generally healthy surgical patient and aren’t using certain related medicines.
CairoAges 21–45 - NCT06355271Recruiting
Pain relief and recovery after planned C-section
This trial studies how well pain is controlled and how quickly women recover after a planned C-section under spinal anesthesia. It compares different pain relief methods to find the best approach.
BellinzonaAges 18 years+ - NCT06364540RecruitingPhase 4
Ketamine vs fentanyl for severe pain in the ER
This trial compares two inhaled pain relievers, ketamine and fentanyl, to see which works better for sudden, severe pain in the emergency room. You would receive one of these medicines through a breathing mask to help your pain quickly.
Brooklyn, New YorkAges 18–120 - NCT06464146RecruitingPhase 3
Comparing nose and mouth pain medicines for broken bones in kids
This study compares three different fast-acting pain medicines given through the nose or by mouth to children with a suspected broken arm or leg in the emergency room. The goal is to find which medicine works best for pain relief within the first hour.
Boulogne-BillancourtAges 2–17 - NCT06498037RecruitingPhase 4
Better fentanyl dosing for cancer pain
This trial is testing a new way to give fentanyl under the skin for cancer-related pain. The goal is to find the right dose quickly and safely to make sure you get enough pain relief.
Rotterdam, South HollandAges 18–120 - NCT06537323Recruiting
Comparing nerve blocks and fentanyl for hip surgery pain
This trial tests different ways to manage pain during hip surgery, comparing a femoral nerve block, a newer nerve block called PENG, and a pain medicine given before surgery. It aims to see which method gives the best pain relief.
CairoAges 55–69 - NCT06759116Recruiting
Comparing two pain medicines for knee surgery recovery
This trial tests whether adding fentanyl or dexmedetomidine to a standard numbing medicine (bupivacaine) provides better pain relief after knee surgery. It may help find the best option for patients undergoing knee procedures like total knee replacement or ACL repair.
El SharkiaAges 21–85 - NCT06966869Recruiting
Fentanyl patch absorption in ICU patients
This study looks at how well fentanyl patches work in ICU patients who are not stable. It aims to understand if the patch is absorbed properly in these patients.
Tel Aviv, IsraelAges 18–70
What Fentanyl is being studied for
Conditions with recruiting Fentanyl studies.
Common questions
- Are there clinical trials studying Fentanyl?
- Yes. Clin2 currently lists 60 recruiting studies that include Fentanyl, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Fentanyl trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Fentanyl an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Fentanyl or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.