Predicting nerve damage from paclitaxel for stomach cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study looks at whether a common chemotherapy drug called paclitaxel (Taxol) causes nerve damage (peripheral neuropathy) in people with advanced stomach cancer. The goal is to find out who is most likely to get this side effect, so doctors can better protect patients during treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stomach cancer (adenocarcinoma) that cannot be removed by surgery or has come back after treatment.
- You are 20 years old or older.
- You are able to take care of yourself (walking and doing daily activities with some help is okay).
- You have tried a first round of chemo that included drugs like 5-FU or capecitabine plus a platinum drug (cisplatin or oxaliplatin), and it either stopped working or caused side effects you couldn't handle.
- You have tumors that can be seen on a CT scan or MRI.
- You do NOT have serious health problems like uncontrolled heart disease, diabetes, or bleeding, and you do not have a history of severe allergic reactions or drug allergies.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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