Clin2
NCT06511765Possibly a fitRecruiting

Nerve block for acute lower back pain: a pilot study

Lumbago

Part of Pain clinical trials.

This study tests whether a single injection of a numbing medicine (ropivacaine) into the muscles of the lower back can quickly relieve sudden, severe back pain that has lasted less than a week. The goal is to see if this nerve block can help when standard pain pills aren't working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
40 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have had lower back pain for less than 7 days, and it hasn't been helped by pain relievers like ibuprofen or naproxen.
  • Your pain is rated 7 or higher on a 0-to-10 scale.
  • You do not have any warning signs (like leg weakness, numbness, fever, or recent injury).
  • You are not taking certain blood thinners (like warfarin or apixaban) and do not have a bleeding disorder.
  • You do not have pain shooting down your leg (sciatica).
  • You are willing and able to come to all study visits and follow the study plan.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07434024Not yet recruiting
Numbing injection for new low back pain

This study tests a numbing injection called an erector spinae plane block to treat sudden low back pain. It may help people who have trouble walking due to their pain and have no known cause for it.

NCT07334288Recruiting
Numbing injection for pain relief after lower back surgery

This study tests a numbing injection near the spine (retrolaminar block) to reduce pain after lower back surgery with hardware. It could help you use less pain medicine and recover more comfortably.

Santiago, Santiago Metropolitan
NCT07180940Recruiting· Phase 4
Comparing two medicines added to a nerve block for back surgery

This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.

Poznan
NCT07397117Recruiting
Ultrasound-guided nerve block for sciatica pain

This trial tests if an ultrasound-guided nerve block can provide better pain relief for sciatica compared to standard care. If you have severe leg pain from sciatica, this study might help you find effective pain control.

San Francisco, California
NCT06666621Recruiting· Phase 4
Naloxone injection for low back pain

This trial tests whether naloxone, a drug that blocks opioid effects, can change how your body responds to pain injections in the lower back. It may help find new ways to treat low back pain that hasn't improved with physical therapy or oral medications.

Nashville, Tennessee
NCT05824338Recruiting· Early Phase 1
Testing ropivacaine spinal anesthesia for lower back surgery

This early study tests whether using ropivacaine (a local numbing medicine) in spinal anesthesia is safe and workable for certain lower back operations. If you qualify, it may help doctors refine anesthesia choices for your type of surgery.

New Westminster, British Columbia

Hear when a new Lumbago trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.